They do have different effects, but you will always draw the same ones every time. You draw one set at 0s, set two at 60s, and then back to set one at 120s and you repeat. The cards in each set are the exact same 4, every single time, with no variance whatsoever. Even if the effects are different, knowing exactly what you are going to draw ahead of time entirely defeats the purpose of having them be called 'cards' in the first place, because they just do not function like them anymore. They're cards only in name and vfx, not mechanically. EW cards have more in common with SB cards than DT cards will have with any of them. Bc the common thread between AST reworks has always been 'you need to play around what you get, not what you always have'. Now you always have everything.
Like... what difference does it make if the 'curative' card is a flat potency heal on one set, and a nice regen on the other? Even if the sets have different buttons, that doesn't change the fact that there's no real thought that goes into them. You either use them somewhere, or you don't, but there's no way to get rid of a card you don't want like royal road or to mitigate the RNG with redraw or to make do with your draw. It's either the fight needs you to use X tool at X time, or it doesn't. And if it doesn't, you press the drawtherflow button at 60s and just overcap it, or you throw the card into the void. You press your dps button at the same time, on the same people. You'll use your designated mit button at the same time, on the same people. You'll use your designated heal button at the same time, on the same people, or you'll keep it as 'insurance' instead of using your third ED charge and not need it most of the time.