It's interesting that Eve is brought up, since the Eden story is a kind of theodicy to explain why evil and suffering exists in the world at all; in Eve's case, it's because a woman was led astray and disobeyed god.

But Venat isn't really meant to be responsible for the existence of suffering, suffering is an extant part of life, she does not say people 'should' suffer as some kind of moral imperative or punishment for their sins, she is saying that they already do, and that they should acknowledge it. I wonder if part of this tension comes from a western audience trying reckon with a very Buddhist view of the nature of suffering that Endwalker presents.