Idk I ended up running Holminster a few times due to many low lvl reapers in queue for example and there were 10+ mobs in some pulls. I played Diurnal AST prior so it made sense to keep a shield on the tank like I kept regen on them as AST. After applying dots to the bigger mobs and using charges of Phlegma before anything else I used Toxikon on whatever was left and spammed Dosis with 2 or less mobs remaining. There were few times where enough mobs and time was left to spam Dyskrasia. It felt like scathe to me where I'd try to avoid being in situations where I should use it.