Cometeor spam, it's too easy to kill someone with Sleep/Bind from a safe distance, kills lead to a faster filling adrenalin bar leading to more Cometeors. It's not so much a problem with melee jobs as they don't have the 'safe distance'.

If 2 teams go against 1, there's just no way you can counter anything. Too many targets to interrupt, Cometeors wiping out your alliance in a minute or less.

Cometeor needs its damage distributed the more targets it hits or have diminishing return.
It might be just me but if you think about it, it takes 2-3 people to wipe out 48, assuming both enemy teams are stacked, having many melee jobs and are busy fighting against each other.