Making sure that your Straight Shot buff is up before reapplying DoTs is pretty handy. For an opener, I highly recommend using the one I've posted. With my current raid setup, I usually average around 500+ using that opener.

After the opener, keeping Straight Shot up for DoT reapplication boosts the chances of getting those Bloodletter resets. If you're lucky enough, you'll get two resets between GCDs which is, for lack of a more subtle word, orgasmic.

Good luck, Saseal! May your arrows fly true!