It can definitely be less accurate depending on a whole slew of factors, but it's also the time when the numbers actually matter. A Simulation just pulls what it thinks your crit rate should be from probability too, when probability does not actually exist within the game. I still haven't crit on Asclepius using the tidal wave book which is pretty disappointing.

Though the BiS lists come down to nearly the same stats anyway since we just swap like 3 pieces to go from det to crit while keeping accuracy