I'm in the camp that I think Calyx, and Preservation are going to be defeated in Dawntrail, but what they know, and will do will have lasting repercussions on the story. I think Calyx gained his knowledge of the shard system from memories that have been seared onto the Dimensional Key because Venat used it to sunder the world. We know it has some Azem magic on it, but there is the possibility that it's not our Azem's magic. And we know the crystal is capable of dimensional travel, and fusion so it could be possible that it is able to sunder dimensions as well.