I think Yoshi-P unintentionally performed something of an 'own goal' on that front by encouraging players to compare her to Emet-Selch.
He was very much framed as an antagonist but the word 'villain' was used to describe him at various points and even during some of the interviews released during Shadowbringers.
Ultimately he was pushed as justified or unforgivable based on the personal opinion of any given individual player. On the basis of judging him for the events he is responsible for during the story.
Which is another reason why this all makes very little sense to me. Now that we know that Venat is responsible for the Sundering as an intentional act and also indirectly responsible for everything that the Ascians did and suffered through...then I remain baffled as to why there's an insistence that she couldn't possibly be a villain.
She very much is one from the perspective of the majority of the Ancients and I think it's time that more writers realised that it is ultimately the players themselves who have the ultimate say on how they feel about any given character.
...and yet how many times would the Sundered have realistically engineered their own demise had they not conveniently had every possible plot device in their favour and minimal meaningful stakes at every turn? I'm reluctant to blame the Ancients as a whole for the actions of subversive ideologues and somehow I doubt the same logic would ever be applied elsewhere in the story. Should the Domans be wiped out because of what Yotsuyu did? Should the Domans be wiped out because of what they did to Yotsuyu in order to make her that way? I don't think so - and I don't think the Ancients deserved to be wiped out either.
I'm also not oblivious to the unfortunate fact that many ideologues in the real world giggle and twitch at the thought of claiming that someone is 'perfect', 'wealthy' or 'stuck up' even if that isn't even the case only to fantasise about those individuals or groups losing every last thing that they care about, including their very lives and that of their loved ones.
There's a much more dangerous variant, however - those that hide their intentions behind tears and the famous words of 'there was no other option'. Which is pretty much Venat to a large degree.