I can see the Scions disbanding, while Estinien just joined he's still the lone wolf type and is there to see this through to the end.

Graha and Alisaie are most likely candidates to stick with us since Graha is new and Alisaie is basically a WOL groupie. Yshtola seems to be the "mascot" of XIV so it wouldn't quite feel the same if she just retires into a cave like the other Matoya. She is way too outgoing to just keep her nose in the books. Even as free agents they will still play some kind of role since they are Trusts, though new blood to expand the roster would be nice.

I've thought about some of the job quest people coming along, like the Viera healer from the GNB questline.

Still curious what they're going to do for the new story. If primals are going to be a thing of the past, what next? Supernatural? Mythological Gods come back to--oh wait, that's the new 24 man.