There's a set of logs in Academia Adynar that describe the development of the Sound. And how it "moved" from one location to another, driving Creation Magic crazy as it went. Amarot was just the last place it ended up. We also still have no idea what caused the Sound. And so far nothing links it back to Creaton Magic as a source of it. Just that Creaiton Magic going crazy was an effect.

The effect of the Sound itself is... interesting. In that it didn't make Creation Magic not work, but rather made it work too well. Instead of having to focus on creating anything, people would spontaneously make things they imagined... specifically things they were afraid of. And anyone with an imagination can see one thing and think of something more terrifying than it. So the Sound was a snowballing problem that... realistically... I don't know how it would be stopped.