While there are some cultural norms (which would then require we ask, which culture?), the concept of finding someone handsome are beautiful is a bit of a personal preference thing.

I think Zero comes across feminine to me, and handsome isn't a word I'd immediately think of when seeing her. But maybe it's because of her strong vocal performer. Zero is genderless to me the same way Liara is genderless to me in Mass Effect lol.

I think Vrtra could be considered handsome in a prettier way, and the FFXVI image in a rugged way. But, I'm sure there are a variety of preferences and types of characters. A lot of people are bored of the standard video game "rugged male" protagonist, others still enjoy it.

I guess my overall point is there probably is not a consensus of the types of characters people desire. I like the variety of different types in XIV and I don't really need to find every character attractive.