I set it up so i can do the entire rotation minus CDs with minimal hotbar switching.
I have all my frequently used skills on the same spot, and if i press L while holding R (which im doing most of the time) it switches to other often used skills. i also put frequently used cooldowns on the L side of my hotbar so that i can see them and keep track of them.

For instance i put despair on the same button as fire 4 but with L added to switch hotbar. Similarly I can also do the entire aoe rotation with only 2 of buttons (minus L).

I also put role skills + limit break in my WXHB hotbar so that theyre mapped to the same spot in all the jobs i use without moving too many things around.

the weird part is my L+R setup which is almost identical to R+L but i figured i had to put blizzard 1 and blizzard 2 somewhere... just in case i got level synced i guess.