A complete combo from Enchanted Riposte all the way to Scorch consumes 160 mana, refunds 35 mana, and deals 2270 potency, and takes (base) 10.2s. In 10.2s of single target spellcasting, you could have dealt 1162.8 potency, and generated 37.74 mana.
Jolt II: 250 potency, 6 mana
Veraero/Verthunder: (310 potency and 11 mana) + 50% chance to boost the next Jolt by (20 potency and 3 mana) ==> 320 potency and 12.5 mana
One dualcast is worth 570 potency and 18.5 mana over (base) 5.0s. In 10.2s the expected values are 1162.8 potency and 37.74.
This means that a complete combo deals (base) +1107.2 potency and costs 162.74 mana, and the mana is worth +6.8 potency per mana.
Enchanted Reprise consumes 20 mana, deals 220 potency, and takes 2.2s. In 2.2s of spellcasting, you could have dealt (base) 250.8 potency and generated 8.14 mana. This means E.Reprise deals -30.8 potency and costs 28.14 mana. We expect 28.14 mana to deal +191.352 potency, so using E.Reprise in general is a loss of 222.152 potency per use.
In re: (1)
In the specific scenario where you have 60|60 and Manafication is within 3s of cooling down, we don't care about E.Reprise's waste of manapotency, because that mana would have been wasted upon Manafication anyway, so all we have to look at is its actual potency vs the spellcasting potency. In 2.2s of spellcasting, you could have dealt (base) 250.8 potency, so E.Reprise would have to deal at least this much for it to be a gain when used as a mana dump before Manafication. However, since it only does 220, Jolt II is (base) equal in value in this scenario. And since Jolt is affected by spell speed, it turns out to be worth slightly more. To be clear, I'm saying that casting Jolt II, not dualcasting anything, and activating Manafication would be as-good-or-better-than using E.Reprise. (But also to be clear, I'm not saying you should cast Jolt II without dualcasting anything--dualcast something, then activate Manafication)
In re: (2)
If Manafication isn't going to come off cooldown by the time the boss is targetable again, the answer is a hard no, as any use of E.Reprise that does not involve specifically dumping mana prior to Manafication is a 222 potency loss. If Manafication is going to come off cooldown by the time the boss is targetable again, and you don't even have time to cast JoltII/Veraero/Verthunder, and you don't have Swiftcast available, then yes, using E.Reprise will be better than doing nothing. If you have Swiftcast available, a Swiftcast-Verslowspell takes the same amount of time to activate as E.Reprise and deals more damage.


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