I think the issue is currently the only way that SE will do anything about botting is for the botter to admit they are botting.

Imagine if you could just rob banks all day and have literally no chance of any negative consequences as long as you never said out loud "I rob banks."

No one would ever get caught because all you have to do is not give yourself up.

I think when you have the overwhelming amount of evidence that exists against some of these botters (I'm passively familiar with the Cactuar one Bourne mentioned, there is a lot and its very obvious) then SE is obligated to dive a bit deeper.

Send them a random GM tell, see how long it takes for a response. Test the waters at least. Destroying ingame economies has a negative impact on player experience and SE should care about that.

Edit: Also I think if word got out that a few of these people experienced real consequences many others would fall in line or be discouraged from continuing.