You don't need to have a 100% Regen/Medica II uptime.
Well, Regen is debatable. As long as the tank is getting hit in the face, yes, have a constant Regen uptime on them and throw rocks at the boss or spam Holy @ trash pulls while it ticks. Medica II, however, definitely doesn't need a 100% uptime, even if it stacks with Regen on the tank. Regen alone is usually enough to keep the tank up to healthy HP levels, and when they dip below your comfort zone you have Tetragramatton and Benediction to save them.
Asylum stacks with everything else, and it's actually quite handy to put it down on the tank during dungeon trash pulls. You can try and use it to heal partywide attacks in dungeon bosses, but in Duty Finder most ranged DPS won't get in the bubble because... idfk.



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