To some people this difference in queue window won't matter, but for people who have trouble pressing their buttons at specific times, a larger queue window might mean the world. So I'd recommend giving macros a try, as they still allow actions to be queued, but if the amount of queue window you're getting from them is below what you need to feel comfortable and/or effective, know that in this case using a non-macro will probably give you a better experience!
No, this is what it's all about. This is what will make you drift. This is literally the exact reason why balance advises to not macro GCDs.