I think the most..hmm..impacting? moment to me was in Final Fantasy Tactics, when Ovelia stabs Delita, and he stabs her back. I felt sorry for Ovelia because during her whole life she has been used, and even by Delita who claimed to really care for her, which he might have, but ended up using her anyway. So, from that point of view, you have 2 tragedies, the first being the death of a character who could only be used, and the death of another character who only could use people, even if he cared for them.

For me, that scene really spoke something.