I don't know if a font change would be possible though it would be nice. It's driven me nuts at times. I would also like to see the objective moved to the top of the window where it will always be visible instead of being buried at the bottom below the description. Some of those descriptions are very long.

As a workaround you could try changing the leve window scale. It does help a bit with legibiity though it also causes the window to take up more of your screen. Right clicking the upper right hand corner of the list side of the leve and journal windows will give you the scale options (60-200%). PS4/PS5 users will want to enable the virtual mouse to do this.