Just to be clear, Fire III > 3x Fire IV > Despair is far worse than a Blizzard IV rotation. However, a macrorotation with fire phases consisting of 4x, 4x, and 3x Fire IVs still comes out ahead of always casting Blizzard IV.
The best practice would probably be to use Blizzard IV and 6 Fire IVs on the rotations where you don't have Polyglot (roughly every third rotation). In this case, you need to make sure you use Fire and get the extra Fire IVs; Blizzard IV with only 4x Fire IVs is worse than skipping Blizzard IV and only getting 3x Fire IVs.



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