Growing up, we couldn't afford getting consoles so PC games with keyboard+mouse are what I'm most natural at.
Nowadays, I do use controller on some games. I've tried it with XIV for a while. But the lack of muscle memory (slow at pressing the trigger+buttons) makes me uncomfortable to use it during combat. I just use controller when gathering.

My keybinds usually includes the number pads and Home/Insert/Delete/etc plus the 2 side buttons on my mouse.
I wish I can get an MMO mouse but I have small asian hands. lol Those I've found (that I can try hand held it in person) seems too big.