Quote Originally Posted by OmegaStrongtan View Post
Does the hotbar change macro have the problem of not queening your skills?
No, but as

Quote Originally Posted by HeavensSword View Post
If the skill is being used in the macro, it will have a queuing issue. If there is a separate macro that only switches the macro palette, then no, but you are now introducing an extra action you have to perform essentially.
pointed out, you have to press the same button at least twice to activate a skill (at least the ones that have a /chotbar change 1-5 macro. If you're a precision type of player that only presses a button to activate a skill once, you wont be able to use this style of setup. But if you're the mashing type of player like me, your thumb will not play any differently, you'll just switch sets around manually way less. For single targets you'll end up with 2 sets (1 is a double hold) and the R1 for resets.