Quote Originally Posted by Urthdigger View Post
You'll want to at least finish the 2.0 story (ending with Praetorium) as a LOT opens up. After that it's mostly unlocking dungeons, working on your relic (no reason not to get the ilvl 90 version, though it's understandable to stop there), and gearing up. You'll also want to continue through the story for various other unlocks (you generally need to be on top of the story and major sidequests to do extreme and trial roulette, two of the better tomestone methods.
What about the alternate classes? I'm working on them, but does anything change or them?