SMN target swap - how many GCDs to break even?

[Havenchild]

Additionally on the subject, regardless of add uptime, if there are 4 or more targets, it is most efficient to drop Bio2 from the adds entirely.

For an example, hourglasses in WoD, or nails in Ifrit. the most efficient use of your dots will actualyl be Misam, Bio, next target Miasma Bio, etc, returning to the original target to reapply Bio then Miasma.
I think Bio 2 is only efficient given the add lasts for longer periods, and there are no more adds to continue dealing with. There are very few of these situations in game that I can think of that this occurs where the add has a sufficient uptime window to allow your dots to run their duration without some sort of consequences, in which case Bio 2 would be applied mostly due to increased potency for whatever duration the add exists, and further to increase potency of Fester.

You gave a bad example. The WoD hourglasses on average will last over 9 seconds which is when Bio 2 begins to go + over a single ruin. Something that would die fast you should forgo DoTs according to the mobs HP and general speed of decline. The faster it dies, the more you forgo. Assuming 9 - 12ish seconds lifetime, you are already in the positive over Ruin Is. Panda's OP post is correct.

Using your example, Ifrit Nails which die extremely fast you would, drop Bio 2 altogether however that's more on nails your other DPS are rotating on. If you were to consider that Ifrit's nails that can be baned onto and nails your other DPS aren't currently hitting, Bio 2 should be used because unless it gets killed by a DPS in the area, those DoTs will run a positive duration.

The case changes slightly when you talk about something that needs to be burned asap. It all really depends on what in question needs to die.

To an extent even if you don't have Fester and something is kinda meaty and needs to die fast, IE: T8 Dreadnaught, even if you don't get the full duration, you should still use all three DoTs as you cannot Bane onto it either.

Which also leads to my next point of the number crunching in this thread in regards to using what. All of this changes in real time, depending on your fellow DPS no?