Level 49 miner ...mining unspoiled nodes?

[Eye_Gore]

You get truth at 46 so you can see the node. You can attempt mining it but you won't get anything out of it. Its all out of reach until you get toil at 50.

[Highwilds]

You can reach the items without the Toil but you'll waste attempts digging them reachable depending how high gathering one has.

[Ashkendor]

You get truth at 46 so you can see the node. You can attempt mining it but you won't get anything out of it. Its all out of reach until you get toil at 50.

You certainly can get something out of it, just not nearly as much as you can after level 50.