My view on the MP efficiency and GCD efficiency is that by taking advantage of buffs as much as possible you can minimize the healing that you have to do to DPS. I don't use 8 healing spells with Divine Seal either, and usually do the same Medica II/Regen and maybe 1 Cure II and then switch to cleric stance, but the idea is that by using SC->PoM->DS->M2->Cleric Stance and then end with regen, you still get the same amount of GCDs because medica 2 will be instant and cleric stance will not affect the next GCD. The many cures in the example are just placeholders for any GCD really.
The actual rotation: SC/PoM/DS/M2/Cleric Stance/AeroII/Aero/Fluid Aura/Stone II/StoneII/Stone II/Cleric Stance off/ Regen (with some more spell speed you can fit in one more stone II).
Also the point of maxing piety is to basically eliminate any use of Cure I and replace it with Cure II so that you can maximize DPS as much as possible by saving GCDs, even using multiple (10+) Holys in a long fight because of your very high MP regeneration. With max piety build you can obtain 6k MP, and really Cure II just completely replaces Cure I. So here we just use the most potent healing to save as many GCDs as possible for Aero/AeroII/Stone II.
My principle is that ending a fight with something like 3K MP isn't that wasteful. Remember that in a long fight like T13 you will have regenerated a lot of MP passively so 3k MP isn't actually that much at all (At least 20k MP to burn through). Ideally we'll have 0 MP by the time we finish, so possible more Holy during add phase/ using only 1 Cure II for earthshakers, healing the MT for flare breath and going straight to cleric stance in the last phase before the next mechanic. But if we have say a 1000 more max MP, that will translate into possibly 5k MP+ (1K + 4K refreshed) in total MP that we could have used for DPS instead.
To put it simply:
The ordinary WHM approach to a tank taking damage worth 2 cures would be to cure twice, but I really don't like tanks being topped off because eos/selene/regen will top off the tank for me, so one cure II is sufficient for me and will buy me 1 GCD. This really adds up I think, so even though Cure II is MP inefficient, it's not that bad and we get to use a lot of DPS spells in the long run and even healing spells too if things get intense.
In terms of overall damage dealt AND healing output, the longer the fight duration goes the better piety scales than any other secondary (det/crit/spellspeed) by using only the most GCD-efficient abilities due to greatly increased MP regen.
But some spell speed (around 470) is really nice because it fits in 1 GCD for Divine Seal/PoM.
Oh and for the damage reduction on defense scaling abilities, open-world monsters are a good way to test this (with/without protect) (with/without foresight on tank/monk or drg or changing gear sets), etc. You can test virus/Str Down/DK as well and will see similar results. The % difference between the averages should be equal to the % reduction in STR/INT.

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