There are actually five rules where the strength of your deck doesn't really matter as much, giving you a huge edge over NPCs: Same, Plus, Swap, Sudden Death, and Reverse. Same and Plus are just easy modes and so easy to exploit. Swap requires luck, but if your * card is swapped for your opponent's ***** card, it really makes the match pretty easy. With Sudden Death, you just need to steal one of your opponent's good cards without losing your good one, and then you just have to tie. Repeat until your deck is all 3-5* cards and your opponent's consists of the worst cards between the two of you. Then, win. Or tie and try again. Reverse means your crappy cards are now amazing - those 13-point * cards are now 31-point cards, and their 28-point ***** cards are now 16-point cards. Yours went from being half as good as theirs to twice as good. It's so easy to beat NPCs with this rule that there are ZERO NPCs that have it as a fixed rule.

Ascension can be easy too - just fill your deck with Beasttribe cards. Early on, four of the * ones plus a mutamix/memroon/frixio/Scarface is really nice. Later, just put all four of the ** beast cards in your deck along with a random 5*. If you have all the cards, switch to using an all scion deck - 4 *** scions and 1 **** scion.

All-Open and Three-Open rules make the game solvable by applying some simple Game Theory (I think there are online apps to do that already?).

The rest of the rules are pointless or irritating. Fallen Ace rarely has an impact. Descension has no impact if no one is using typed cards, and who would if that's the rule, unless you did a Roulette? Order/Chaos are a pain, as is Random as stated above.