Leveling other DoH, what is the best way to make use out of Byregot's Blessing?

[Arale]

Would Great Strides even work with it? It says in the description that it doubles the effectiveness of "touch" actions specifically.

It does work with it, and marvelously well at that. That's how I 1 shot all of my recipes across my crafts. Get 5-7 stacks from basic synthesis, pop great strides, make sure you have steady hand stack available for Byregots, then kaboom.