I think there's pros and cons to keyboard and mouse, and gamepad. Quickly targeting members of your party to heal or cast whatever on them may be easier to do than on pad, but on pad using all 16 abilities on your primary cross hotbar is easier to do than using all 10 of your abilities on your normal hotbar. Keep in mind that in both these cases when I say "easier" I mean "more intuitive." You can do something well even if it doesn't seem intuitive at first. Healers on pad can get really good at scrolling through party members on the fly and removing debuffs and such while moving.

As for the actual PC vs PS3 debate... the PS3 looks a bit worse graphically, and the framerate's terrible, probably half of that of most pc players. Not to mention the culling's worse and the fog. The PS3 is just dramatically less powerful than most PC's these days and it shows.

That said, the game is certainly very playable on PS3, but I don't think the experience is as smooth or pretty as on PC.