you say your running Triple Crossfire but you do not state what graphics cards your using or even your system spec. the game is not optimized for tri-crossfire/sli and i dont know any game that is.

the game runs perfectly fire with dual but the main problem is that AMD drivers are really bad and is commonly the problem. have you tried rolling back to older drivers?

I do not have any problems running the dame in quad SLI, no crashing, no problems at all.

Some more information on your PC spec/config would help others to help you.