As a MRD I have 2 items in my hotbar - hi-potion (could save you long enough to get that vital cure) and an ether (bit odd I know but sometimes that extra flash comes in handy when things are asleep).

I honestly can't think of any other items you'd need in your hotbar.

Food lasts 30m and Esuna should take away anything that's crippling your character.

Just get a decent party / use some strategy instead of relying on items.