Endwalker story doubt: spoiler alert

[Kozh]

And again, we know she was aiming at the planet, because Mare Lamentorum was completely fine.

The lopporits despair (if you even called it that), only start to be noticeable after they are no longer useful after meteion died. And throughout the millenia, they spend a lot of time in hibernation. And it might have be that zodiark barrier also big enough to encompasses the moon.
*Lopporits aren't even the same beastmen as ones in the planet.

The rest of the universe was doing worse as well, but they're not exploding into Blasphemies, so anywhere else was better than there

Each planet has different manifestation of despair. Simply because others might not result in blasphemies, we can't really say it's better. In the end, they all experience the same, which is the planet dying. We saw what happen with Dragon star, and it's the same as etheirys during it's first FD. Where the star couldn't sustain new lives, the wind stop blowing, etc.

but also, an additional point: consider what Venat knew in the first place. Venat was not omniscient, she and her group were working from a limited amount of knowledge. She didn't actually know how the rest of the universe would handle against Meteion's collateral damage, so exactly how badly they're doing doesn't really enter the discussion.

Okay, and?