Loss of Thunder = -5.6% SINGLE TARGET DPS
On average you can use 1 stack of Aetherflow per rotation and you can use Ruin/Ruin II about 3 times between DOTs every rotation. Pet Potency doesn't work exactly when compared to Character Potency DMG isn't so easy to calculate. For example Garuda's 100 Potency attack is about 70% stronger than Ifrit's 120 Potency Attack (not including Ifrit's Auto-Attack). However Ifrit's 120 Potency Attack + Auto-Attack = Garuda's 100 Potency Attack (no Auto-Attack available).
Bio: Potency 40/tick Duration 18s (6 ticks) Total Potency = 240
Miasma: Potency 20 + Potency 35/tick Duration 24s (8 ticks) Total Potency = 300
Bio II: Potency 35/tick Duration 30s (10 ticks) Total Potency = 350
Thunder: Potency 30 + Potency 35/tick Duration 18s (6 ticks) Total Potency = 240
Shadow Flare: Potency 25/tick Duration 30s (10 ticks) Total Potency = 250
Energy Drain: Potency 150
Fester: Potency 300 (max)
Ruin/RuinII x3 (w/Thunder) and x4 (w/o Thunder): Potency 240 and 320
Increase in both 2-4 Target AOE DPS and 5+ Target AOE DPS
In 2.1 the loss of Thunder is replaced with the addition of Blizzard II for SMN. SMN was already the king of non-SR (speed run) AOE, now it's going to help close the gap on SR AOE when compared to other jobs. Before you had to cast Thunder individually on every target to maximize AOE DPS on 2-4 targets (which took up the entire time between your rotation). Now Thunder mutlicast is replaced with Blizzard II and it works very similarly to casting Ruin/Ruin II between DOTs in your rotation. You never really had enough time to cast Thunder on all 4 mobs between rotations.
Bio: Potency 40/tick Duration 18s (6 ticks) Total Potency = 240 (2-4)
Miasma: Potency 20 + Potency 35/tick Duration 24s (8 ticks) Total Potency = 300 (2-4)
Bio II: Potency 35/tick Duration 30s (10 ticks) Total Potency = 350 (2-4)
Shadow Flare: Potency 25/tick Duration 30s (10 ticks) Total Potency = 250 (ALL)
Miasma II: Potency 20 + Potency 10/tick 15s (5 ticks) Total potency = 70 (ALL)
Bane: Potency 0