in any meaningful way? not really; the only difference is on jugulate/mug anyway. you'd mostly always be using viper in raid content, but you can put on wasp to stun adds for 2s on shiva ex and switch back to viper afterwards; and you probably should switch from viper to wasp for dreadknights on t5.
but it's all really minor lol. in open world or dungeons wasp is nice for the stun, for positionals, cc or interrupts (satasha hm first boss if no one else is going to stun for example)
