I'm not going to be aggressive about it, but I am playing with double the ping I usually have to put up with. Going from 170 ms to 300+ is uncomfortable at times. As it is, I have to react to AoE before they happen, if you're in the middle of it forget about avoiding that damage. Titan HM is going to be a treat, I'm sure - but everything so far has been more than manageable.

Of course, as someone said above, PvP isn't going to be super competitive when your opponents have at least half a second on you.