On PC, use gamepad for most things but on dungeon runs I prefer my keyboard (G15) and mouse combo as I find it faster to react for me.

Its not very often I will use the WASD when using my keyboard as I react to moving faster by Right click + Left click + sweep mouse to direction i wanna go, free's the skill bar hand up and you are instantly running (plus the WASD claw really does hurt after a while). *Shrugs* Comes down to personal preference.