Doh, can't use AMD Overdrive with my CPU.

Regardless, I tried those settings from the Catalyst control and the only visually appealing change was changing Texture Filtering from Quality to High Quality. This also dropped my frames in Uld from 45-60 to 25-35.

Also noticed that changing AA settings made the game look blurry (odd) and the font look like an emulator when you set it to Super Eagle.