Apologies in advance for not reading the entire thread but...

To me, it seems like this entire issue could be solved in a very straightforward manner if the Development team were to introduce this measure:

You can only be eligible to lot on a particular boss's drops once per week. This way, guild members can go back and help their other guild members without getting a second crack at loot. This will make it much more PUGable, since you could technically join a group that's further behind if you had confidence they would go all the way. Finally, an entire guild won't find themselves suddenly stuck if a RL emergency claimed a member away from the game for an extended period of time.

Or am I missing something?