As to boss fates. I fought some pugil in Upper Los Noscea last night. I was the only one around and no one in sight. So I engaged it just for a good laugh. To my suprise I was able to solo it to 20% hp... But I failed because I couldn't kill it fast enough and ran out of time. But still got 6,000 exp for trying. He would cast screw driver over and over again and I would just get out of the way and pop my hp drain and +healing buffs and stay over 1000k hp the entire encounter.

Wasn't challenging at all.