I've gotten a crash (this message) once while in game and a couple of times when tabbing out to skype ect to mic with friends while playing. It's not been to bad for me, and I am running the game max settings with a much less expensive rig than you (though we got the same processor i think) Can you Provide a full DXdaig? that could help shed some light

Edit- for me its not happened enough for me to really care, and i figure they'll patch it eventually. but we might be getting the crash for different reasons so, lets try to figure this out