OK. to be clear. a macro like the one below is still a dps loss

/micon "heavy shot"
/ac "heavy shot"

This is because of the queing system explained on this page already. Nobody is perfect and witout using the queing system you are bound to lose a couple tenths of a second at minumum with each ability using macros.

Here is the kicker. Only in game macros are the issue. If you have a button on your mouse or keyboard that hits several keys at once. That still uses the queueing system. For example, Im lazy, and almost always want to use bloodbath, fight or flight, and shelltron on cd as soon as possible. so every time i hit 6 on my naga, it also hits the keys i have associated with those skills on the side of my screen. essentially hitting all 4 at once and still being able to utilize the queueing system built into the game.

Same can, in theory, be applied to bard abilities like bloodletter and ME, but not sure how it will work with the horror that is minuet. Mainly because my bard will sit at 50 until the unlikely event they take away the dam cast bar adn turn it into a buff to damage given for standing still for x ammount of time.