If you cannot get 9GDCs within a Blood for Blood, then the best place to use it is before ID in the opener. This should allow you to hit all of the 180+PPS thresholds. Also, the difference between hitting and not hitting 9 GDCs is around 4PPS on average. Not that much if I may say so.

As for the relic, no clue. I'm currently grinding out as much money as I can and I'm going to go for that 4 acc meld.