I have a good rotation with 2 sets of macro's. I start with a macro that casts poison II, bio II, and dia II. Then I toss up a heal and mash the second macro that consists of paralyze, slow, and blind. While dot's are up as long as I don't have to heal I use blood rite II and then toss a shadowsear, bainsh II, and scourge II. I'm only rank 48 but with this combo I can pretty much take care of any party, and take out nm's.