As a scholar, I have struck a middle-ground on DOT macros.

I use:

/ac Miasma <t>
/wait 2.5
/ac Bio <t>

and

/ac Thunder <t>
/wait 2.5
/ac Aero <t>

The reason I bring these up, is that I find it's useful to have a cast time skill immediately followed by an instant skill. As soon as Miasma casts, you can start moving, and Bio will still go off. Any longer macros with more wait time seem too difficult to pull off, in my opinion. I keep Bio II separate. I keep one set of macros for soloing and one set for healing, the only difference being whether they are <t> or <tt>