I live in western PA with Atlantic Broadband as my ISP. I am experiencing the same issues of S0/R0 after being in game for a minute or so. I can stand in town and not touch a single key/button and watch the game freeze itself. A couple nights ago, somewhere around midnight EST, I was able to be online for much longer until I tried talking to an NPC vendor and then the issues started happening again.
I am about 90% sure it is NOT my ISP though. My friend in the next room is on the same router/internet connection I am and I can play on his computer flawlessly. I am convinced this is something SE must fix on their end.