This is what I plan on doing, though I haven't tested it yet, and obviously throwing in whatever when the situation calls for it.

1. Power Surge - Spineshatter is only 170, so PS is better used here.
2. Jump
3. Feint
4. Phlebotomize
5. Heavy Thrust
6. Combo 2 (Chaos Thrust Combo) - I prefer this combo first because Disembowel's piercing reduction and Chaos Thrust's DoT. By the time these run out you'll be at this combo again.
7. HT
8. Combo 3 (Full Thrust Combo)
Repeat steps 5-7, feel free to throw in a PS->Jump.

Life Surge before a Full Thrust, use Blood for Blood right before your Impulse Drive combo if you feel safe; it should last through Full Thrust. Otherwise, save it for right before your Full Thrust combo.

The average damage output of the Full Thrust combo is 216.67 Potency before apply buffs/debuffs, so I figure it best to use LS/B4B here. I use Spine/Leg Sweep for stuns on boss as a save.