It is very true that this game is seriously lacking in the item interactions department. I can pretty much name everything in the game that can be clicked on in a short list.

Player Characters
Non-Player Characters
The book on the counter that read as ??? in the Conjurer Guild before but now has a name it seems.
The 5 ??? points in Mor Dhona for the Main Storyline Objective
Regional Levequest Chests (Added Later)
Side-Quest Objective Points (Added Later)

I have literally traveled and explored the entire current world and saw some unique stuff but none of it is interactive. Things that are not allowed to be targeted even can include things such as.

Aetheryte Crystals and Aetherial Gates
Summoning Bells
Regional Levequest Objective Points
Gathering Nodes
Ferry Doorways
Manual Operating Doorways (these are incredibly annoying in the dungeons such as Nanawa Mines and Tam-tara Deepcroft)

These things need to be interacted with opening the menu and examining or such to function. My very first day of the game was just getting used to the fact that I could not touch anything in the game besides people and monsters and had to figure out the little ! meant I was suppose to interact through opening my menu when I was in a certain range of things. I remember a time when games would add all sorts of worldly interactions just for clicking purposes and it would tell them something relative or just humorously useless for fun about what was clicked.