I don't expect much but I have some issues with the colour choices that vary in impact for severity by the content and some colour blindness, the deuteranopia setting or the colour blindness settings in general somewhat makes things look weird.

An example with the setting on would be tree logs looking blue/purple with it on for me, no I wasn't looking at trees in the area with blue bananas in dawntrail.
Generally, it's like looking at a new world where everything seems to be in a strange colour that's more different than I expected.

I have two struggles that made me incredibly annoyed to look at, one being something I gave up on and learned by pose which is the buff icon for VPR's flank and rear positionals, they are supposedly green and red, but they look like red and red but darker.
What I think of NIN's positionals are yellow and red which I can identify.

The other recent struggle were the tiles against Zelenia, the tiles are red and red but slightly lighter, I can still spot the borders being faintly white. I believe I can deal with it, but it's just really difficult when it's something so simple solely because I rely on the border to identify the difference of the red tiles.

From what I've heard, it's supposed to be red and grey, but they really just look like red and a faint washed up red.
It would be nice if the difference in colour would be... more different such as red and white.
Mechanic wise, instead of identifying a supposed red and grey, im looking for the borders of a tile as the faint difference for gloom.

I'll take colour blindness setting suggestions, for now, I'd be tinkering with the colours as long as it doesn't have an extreme difference that has an impact on everything else.
Which I somewhat failed as everything looked alien with it on.

I believe it did help with the buff icons as I think it did turn one of them blue? Might've misremembered, but I'd also wish I could pick and choose a colour spectrum preference as some would seem fine while others are abnormal.