Let me start this by breaking down the mathematics of these missions.
Once you have finished leveling your squadron, the optimal use of your weekly priority mission is one of the priority missions that rewards 10 buff items.
There are 9 level-50 priority missions.
Each of these missions has a set of required attributes, pulled from what I will call a "profile index". This profile index is set weekly, affects all missions simultaneously.
There are 6 possible profile indices. It is unclear how this index is chosen, or whether it is distributed among the 3 grand companies (e.g. 2 per GC), so we will assume it is random and that all profiles are available to all GCs (side note, I would appreciate some data gathering to prove this true or false).
Additionally, each mission has either 1, 2, or 3 "Mission Affinities", each of which can a race or class.
For squadrons, there are 9 classes and 6 races.
This comes out to num_missions * num_profiles * (affinities + affinities^2 + affinities^3)
= 9 * 6 * (9+6 + (9+6)^2 + (9+6)^3)
= 195210
Let's move to classes. To optimize for higher affinity coverage, my strategy is to have 8 diverse jobs (leaving one out) and 6 diverse races (with the 2 remaining squadron members being different races). I have also run simulations for non-diverse choices (e.g. all gladiator, etc), but found that this did not otherwise give benefits. This limits our search space to just 9 possibilities (leaving out only one of each job)
As for training, you may have 3 stats, in intervals of 20, summed up to 400. There are 231 possible training configurations.
This leads to 2079 possible squadrons.
Additionally, squadron members may have chemistries. For the purposes of meeting stats, there are really only 3 chemistry effects that matter: (physical, magic, tactical increased by 15%). Let's assume the optimistic case where we can always trigger it (e.g. we have a condition like "all of a different class"). In the case where the race or class of a mission affinity matches the character, this is doubled (30%).
So far I have confirmed via simulations:
There is no combination of training/jobs (including with replacement) with full 15% bonuses (no affinities) that grants you 3 completed stats on any level 50 priority mission under any profile index.
I am still working on simulating different racial combinations + affinities, but it seems like 3-statting might be possible under some conditions.
I was not expecting this system to be so hardcore.