As an American player who plays almost exclusively on the EU side of things because that's where my friends are, I don't have any culture shock issues... much as I never did in fFXI... I will warn players though, that lag and feedback can be awful in end-game content when you are playing on such a far away data center. As long as you don't mind that, there isn't any issue, nor should there be cuurually, unless we all start losing our minds.