Quote Originally Posted by Soukyuu View Post
It's not. It's just different.

Optimize you skill layout and you won't have to do it too often.
Animation lock is negating any advantage keyboard is giving you, except for having more free time.
That is really, really a matter of prefference. My friends all play on controllers (one of them plays exclusively with the keyboard, no mouse) and it's kind of a worn out joke of mine saying something about controllers being bad.
In the end it really only matters regarding what the person is used to, I personally use a nostromo keypad and my mouse, move through the actions bars with the scrolling wheel, select actions with the mouse and that stuff. It's not about gaining performance, it's simply about what feels more comforable on my hands.